Canine D-Dimer
D-Dimer is a specific degradation product of cross-linked fibrin under the action of plasmin.
The content of D-Dimer in normal body plasma is very low. Its increase indicates that fibrinthrombosis and fibrinolysis have occurred in the body.As one of the molecular markers ofhypercoagulability and hyperfibrinolysis in vivo. D-dimer is a sensitive indicator of DIC (disseminated intravascular coagulation) and a marker of systemic thrombosis (such aspulmonary embolism), and its elevation has diagnostic significance for DIC and systemic thrombosis. In addition D-dimer is also a marker of hypercoagulable states such as tumors and heart disease.
Specifications
| Animal | Canine, Feline |
|---|---|
| Sample type | Serum,Plasma |
| Sample volume | 75μL |
| 39-86 °F storage | 24 months shelf life |
| Basically normal | 0-250 ng/mL |
| Thrombosis cannot be ruled out | 250-1000 ng/mL |
| Thrombus or DIC may be present and further examination is required | >1000 ng/mL |
Operational Steps
Sample Preparation
Add 75 µL of serum or plasma sample into the buffer tube.
Mix thoroughly without forming bubbles.
Sample Application
Transfer 75 µL of the prepared mixture into the sample well of the test card.
Result Analysis
Insert the test card into the Healvet 3000 Analyzer with standard test mode.
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